Soul, gospel and blues legend Etta James has been pronounced terminally ill by her live-in doctor, our colleagues at The Huffington Post report. James, who is best known for her classic rendition of 'At Last,' was diagnosed with leukemia earlier this year, and the illness was declared incurable by her physician two weeks ago.

The 73-year-old singer has been suffering from various ailments in recent years. In May, the iconic singer was hospitalized with a urinary tract that led to sepsis. She has sought out treatment for substance abuse several times and, in January 2010, her husband revealed that she was suffering from leukemia and dementia.

Her doctor, Elaine James -- no relation -- asked that concerned fans pray for the singer in her time of need. "I am Southern and Christian and would just ask for the prayers of her fans and friends," the doctor told the Riverside Press-Enterprise. "They know she's been sick, but not how sick."

James, who was born Jamesetta Hawkins, was inducted into the Rock and Roll Hall of Fame in 1993, won four Grammys and left an indelible mark on music history.